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Cell death following the loss of ADAR1 mediated A-to-I RNA editing is not effected by the intrinsic apoptosis pathway

Modifications of RNA, collectively termed as the epitranscriptome, are widespread, evolutionarily conserved and contribute to gene regulation and protein diversity in healthy and disease states. There are >160 RNA modifications described, greatly exceeding the number of modifications to DNA. Of t...

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Pubblicato in:Cell Death Dis
Autori principali: Walkley, Carl R., Kile, Benjamin T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6892865/
https://ncbi.nlm.nih.gov/pubmed/31801951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-2160-6
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