Editing independent effects of ADARs on the miRNA/siRNA pathways

Adenosine deaminases acting on RNA (ADARs) are best known for altering the coding sequences of mRNA through RNA editing, as in the GluR-B Q/R site. ADARs have also been shown to affect RNA interference (RNAi) and microRNA processing by deamination of specific adenosines to inosine. Here, we show tha...

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Detalhes bibliográficos
Main Authors: Heale, Bret S E, Keegan, Liam P, McGurk, Leeanne, Michlewski, Gracjan, Brindle, James, Stanton, Chloe M, Caceres, Javier F, O'Connell, Mary A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2735678/
https://ncbi.nlm.nih.gov/pubmed/19713932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.244
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