Membrane and synaptic defects leading to neurodegeneration in Adar mutant Drosophila are rescued by increased autophagy

BACKGROUND: In fly brains, the Drosophila Adar (adenosine deaminase acting on RNA) enzyme edits hundreds of transcripts to generate edited isoforms of encoded proteins. Nearly all editing events are absent or less efficient in larvae but increase at metamorphosis; the larger number and higher levels...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:BMC Biol
Main Authors: Khan, Anzer, Paro, Simona, McGurk, Leeanne, Sambrani, Nagraj, Hogg, Marion C., Brindle, James, Pennetta, Giuseppa, Keegan, Liam P., O’Connell, Mary A.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7020516/
https://ncbi.nlm.nih.gov/pubmed/32059717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-020-0747-0
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados