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Sirtuin 5 Regulates Proximal Tubule Fatty Acid Oxidation to Protect against AKI

BACKGROUND: The primary site of damage during AKI, proximal tubular epithelial cells, are highly metabolically active, relying on fatty acids to meet their energy demands. These cells are rich in mitochondria and peroxisomes, the two organelles that mediate fatty acid oxidation. Emerging evidence sh...

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Dades bibliogràfiques
Publicat a:J Am Soc Nephrol
Autors principals: Chiba, Takuto, Peasley, Kevin D., Cargill, Kasey R., Maringer, Katherine V., Bharathi, Sivakama S., Mukherjee, Elina, Zhang, Yuxun, Holtz, Anja, Basisty, Nathan, Yagobian, Shiva D., Schilling, Birgit, Goetzman, Eric S., Sims-Lucas, Sunder
Format: Artigo
Idioma:Inglês
Publicat: American Society of Nephrology 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6900790/
https://ncbi.nlm.nih.gov/pubmed/31575700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2019020163
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