Structure‐Based Screening of Tetrazolylhydrazide Inhibitors versus KDM4 Histone Demethylases

Human histone demethylases are known to play an important role in the development of several tumor types. Consequently, they have emerged as important medical targets for the treatment of human cancer. Herein, structural studies on tetrazolylhydrazide inhibitors as a new scaffold for a certain class...

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Bibliografiske detaljer
Udgivet i:ChemMedChem
Main Authors: Małecki, Piotr H., Rüger, Nicole, Roatsch, Martin, Krylova, Oxana, Link, Andreas, Jung, Manfred, Heinemann, Udo, Weiss, Manfred S.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
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Full Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6899576/
https://ncbi.nlm.nih.gov/pubmed/31475772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201900441
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