Structure‐Based Screening of Tetrazolylhydrazide Inhibitors versus KDM4 Histone Demethylases

Human histone demethylases are known to play an important role in the development of several tumor types. Consequently, they have emerged as important medical targets for the treatment of human cancer. Herein, structural studies on tetrazolylhydrazide inhibitors as a new scaffold for a certain class...

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Bibliografski detalji
Izdano u:ChemMedChem
Glavni autori: Małecki, Piotr H., Rüger, Nicole, Roatsch, Martin, Krylova, Oxana, Link, Andreas, Jung, Manfred, Heinemann, Udo, Weiss, Manfred S.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2019
Teme:
Full Papers
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6899576/
https://ncbi.nlm.nih.gov/pubmed/31475772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201900441
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