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Extended Recognition of the Histone H3 Tail by Histone Demethylase KDM5A
Human lysine demethylase KDM5A is a chromatin-modifying enzyme associated with transcriptional regulation, because of its ability to catalyze removal of methyl groups from methylated lysine 4 of histone H3 (H3K4me3). Amplification of KDM5A is observed in many cancers, including breast cancer, prosta...
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| Publicado en: | Biochemistry |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7207076/ https://ncbi.nlm.nih.gov/pubmed/31985200 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.9b01036 |
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