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Substrate recognition and processing by γ-secretase
The γ-secretase complex is composed of four membrane protein subunits, including presenilin as the catalytic component with aspartyl protease activity. The enzyme cleaves within the transmembrane domain of >70 different type I integral membrane proteins and has been dubbed “the proteasome of the...
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| Udgivet i: | Biochim Biophys Acta Biomembr |
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| Hovedforfatter: | |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6899174/ https://ncbi.nlm.nih.gov/pubmed/31295475 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2019.07.004 |
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