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Structure and Function of the γ‑Secretase Complex
γ-Secretase is a membrane-embedded protease complex, with presenilin as the catalytic component containing two transmembrane aspartates in the active site. With more than 90 known substrates, the γ-secretase complex is considered “the proteasome of the membrane”, with central roles in biology and me...
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| Publicado no: | Biochemistry |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6618299/ https://ncbi.nlm.nih.gov/pubmed/31198028 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.9b00401 |
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