Cargando...
Transmembrane substrate determinants for γ-secretase processing of APP CTFβ
The amyloid β-peptide (Aβ) of Alzheimer’s disease (AD) is generated by proteolysis within the transmembrane domain (TMD) of a C-terminal fragment of the amyloid β protein-precursor (APP CTFβ) by the γ-secretase complex. This processing produces Aβ ranging from 38 to 49 residues in length. Evidence s...
Guardado en:
| Publicado en: | Biochemistry |
|---|---|
| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2016
|
| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5539764/ https://ncbi.nlm.nih.gov/pubmed/27649271 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00718 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|