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PRDM16 maintains homeostasis of the intestinal epithelium by controlling region-specific metabolism

Metabolic pathways dynamically regulate tissue development and maintenance. However, the mechanisms that govern the metabolic adaptation of stem or progenitor cells to their local niche are poorly understood. Here, we define the transcription factor PRDM16 as a region-specific regulator of intestina...

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Détails bibliographiques
Publié dans:Cell Stem Cell
Auteurs principaux: Stine, Rachel R., Sakers, Alexander P., TeSlaa, Tara, Kissig, Megan, Stine, Zachary E., Kwon, Chan Wook, Cheng, Lan, Lim, Hee-Woong, Kaestner, Klaus H., Rabinowitz, Joshua D., Seale, Patrick
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6898778/
https://ncbi.nlm.nih.gov/pubmed/31564549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2019.08.017
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