PRDM16 maintains homeostasis of the intestinal epithelium by controlling region-specific metabolism

Metabolic pathways dynamically regulate tissue development and maintenance. However, the mechanisms that govern the metabolic adaptation of stem or progenitor cells to their local niche are poorly understood. Here, we define the transcription factor PRDM16 as a region-specific regulator of intestina...

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Detalhes bibliográficos
Publicado no:Cell Stem Cell
Main Authors: Stine, Rachel R., Sakers, Alexander P., TeSlaa, Tara, Kissig, Megan, Stine, Zachary E., Kwon, Chan Wook, Cheng, Lan, Lim, Hee-Woong, Kaestner, Klaus H., Rabinowitz, Joshua D., Seale, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6898778/
https://ncbi.nlm.nih.gov/pubmed/31564549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2019.08.017
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