NOS1 inhibits the interferon response of cancer cells by S-nitrosylation of HDAC2

BACKGROUND: The dysfunction of type I interferon (IFN) signaling is an important mechanism of immune escape and metastasis in tumors. Increased NOS1 expression has been detected in melanoma, which correlated with dysfunctional IFN signaling and poor response to immunotherapy, but the specific mechan...

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書目詳細資料
發表在:J Exp Clin Cancer Res
Main Authors: Xu, Pengfei, Ye, Shuangyan, Li, Keyi, Huang, Mengqiu, Wang, Qianli, Zeng, Sisi, Chen, Xi, Gao, Wenwen, Chen, Jianping, Zhang, Qianbing, Zhong, Zhuo, Lin, Ying, Rong, Zhili, Xu, Yang, Hao, Bingtao, Peng, Anghui, Ouyang, Manzhao, Liu, Qiuzhen
格式: Artigo
語言:Inglês
出版: BioMed Central 2019
主題:
Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6896289/
https://ncbi.nlm.nih.gov/pubmed/31805977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1448-9
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