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NOS1 inhibits the interferon response of cancer cells by S-nitrosylation of HDAC2
BACKGROUND: The dysfunction of type I interferon (IFN) signaling is an important mechanism of immune escape and metastasis in tumors. Increased NOS1 expression has been detected in melanoma, which correlated with dysfunctional IFN signaling and poor response to immunotherapy, but the specific mechan...
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| Publicat a: | J Exp Clin Cancer Res |
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| Autors principals: | , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6896289/ https://ncbi.nlm.nih.gov/pubmed/31805977 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1448-9 |
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