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Necessities in the Processing of DNA Double Strand Breaks and Their Effects on Genomic Instability and Cancer

Double strand breaks (DSBs) are induced in the DNA following exposure of cells to ionizing radiation (IR) and are highly consequential for genome integrity, requiring highly specialized modes of processing. Erroneous processing of DSBs is a cause of cell death or its transformation to a cancer cell....

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發表在:Cancers (Basel)
Main Authors: Iliakis, George, Mladenov, Emil, Mladenova, Veronika
格式: Artigo
語言:Inglês
出版: MDPI 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6896103/
https://ncbi.nlm.nih.gov/pubmed/31661831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11111671
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