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Necessities in the Processing of DNA Double Strand Breaks and Their Effects on Genomic Instability and Cancer

Double strand breaks (DSBs) are induced in the DNA following exposure of cells to ionizing radiation (IR) and are highly consequential for genome integrity, requiring highly specialized modes of processing. Erroneous processing of DSBs is a cause of cell death or its transformation to a cancer cell....

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Iliakis, George, Mladenov, Emil, Mladenova, Veronika
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6896103/
https://ncbi.nlm.nih.gov/pubmed/31661831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11111671
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