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Necessities in the Processing of DNA Double Strand Breaks and Their Effects on Genomic Instability and Cancer

Double strand breaks (DSBs) are induced in the DNA following exposure of cells to ionizing radiation (IR) and are highly consequential for genome integrity, requiring highly specialized modes of processing. Erroneous processing of DSBs is a cause of cell death or its transformation to a cancer cell....

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Bibliografiske detaljer
Udgivet i:Cancers (Basel)
Main Authors: Iliakis, George, Mladenov, Emil, Mladenova, Veronika
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6896103/
https://ncbi.nlm.nih.gov/pubmed/31661831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11111671
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