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PIK3CA Cooperates with KRAS to Promote MYC Activity and Tumorigenesis via the Bromodomain Protein BRD9

Tumor formation is generally linked to the acquisition of two or more driver genes that cause normal cells to progress from proliferation to abnormal expansion and malignancy. In order to understand genetic alterations involved in this process, we compared the transcriptomes of an isogenic set of br...

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Bibliografske podrobnosti
izdano v:Cancers (Basel)
Main Authors: Bell, Catherine M., Raffeiner, Philipp, Hart, Jonathan R., Vogt, Peter K.
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6896067/
https://ncbi.nlm.nih.gov/pubmed/31652979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11111634
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