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PIK3CA Cooperates with KRAS to Promote MYC Activity and Tumorigenesis via the Bromodomain Protein BRD9

Tumor formation is generally linked to the acquisition of two or more driver genes that cause normal cells to progress from proliferation to abnormal expansion and malignancy. In order to understand genetic alterations involved in this process, we compared the transcriptomes of an isogenic set of br...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Bell, Catherine M., Raffeiner, Philipp, Hart, Jonathan R., Vogt, Peter K.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6896067/
https://ncbi.nlm.nih.gov/pubmed/31652979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11111634
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