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Structural Implications of STAT3 and STAT5 SH2 Domain Mutations
Src Homology 2 (SH2) domains arose within metazoan signaling pathways and are involved in protein regulation of multiple pleiotropic cascades. In signal transducer and activator of transcription (STAT) proteins, SH2 domain interactions are critical for molecular activation and nuclear accumulation o...
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| Publicado no: | Cancers (Basel) |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6895964/ https://ncbi.nlm.nih.gov/pubmed/31717342 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11111757 |
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