Structural Implications of STAT3 and STAT5 SH2 Domain Mutations

Src Homology 2 (SH2) domains arose within metazoan signaling pathways and are involved in protein regulation of multiple pleiotropic cascades. In signal transducer and activator of transcription (STAT) proteins, SH2 domain interactions are critical for molecular activation and nuclear accumulation o...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cancers (Basel)
Egile Nagusiak: de Araujo, Elvin D., Orlova, Anna, Neubauer, Heidi A., Bajusz, Dávid, Seo, Hyuk-Soo, Dhe-Paganon, Sirano, Keserű, György M., Moriggl, Richard, Gunning, Patrick T.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI 2019
Gaiak:
Review
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6895964/
https://ncbi.nlm.nih.gov/pubmed/31717342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11111757
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