Cobalt protoporphyrin IX increases endogenous G‐CSF and mobilizes HSC and granulocytes to the blood

Granulocyte colony‐stimulating factor (G‐CSF) is used in clinical practice to mobilize cells from the bone marrow to the blood; however, it is not always effective. We show that cobalt protoporphyrin IX (CoPP) increases plasma concentrations of G‐CSF, IL‐6, and MCP‐1 in mice, triggering the mobiliza...

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Publicat a:EMBO Mol Med
Autors principals: Szade, Agata, Szade, Krzysztof, Nowak, Witold N, Bukowska‐Strakova, Karolina, Muchova, Lucie, Gońka, Monika, Żukowska, Monika, Cieśla, Maciej, Kachamakova‐Trojanowska, Neli, Rams‐Baron, Marzena, Ratuszna, Alicja, Dulak, Józef, Józkowicz, Alicja
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6895613/
https://ncbi.nlm.nih.gov/pubmed/31709729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201809571
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