Cobalt protoporphyrin IX increases endogenous G‐CSF and mobilizes HSC and granulocytes to the blood

Granulocyte colony‐stimulating factor (G‐CSF) is used in clinical practice to mobilize cells from the bone marrow to the blood; however, it is not always effective. We show that cobalt protoporphyrin IX (CoPP) increases plasma concentrations of G‐CSF, IL‐6, and MCP‐1 in mice, triggering the mobiliza...

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Detalhes bibliográficos
Publicado no:EMBO Mol Med
Main Authors: Szade, Agata, Szade, Krzysztof, Nowak, Witold N, Bukowska‐Strakova, Karolina, Muchova, Lucie, Gońka, Monika, Żukowska, Monika, Cieśla, Maciej, Kachamakova‐Trojanowska, Neli, Rams‐Baron, Marzena, Ratuszna, Alicja, Dulak, Józef, Józkowicz, Alicja
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6895613/
https://ncbi.nlm.nih.gov/pubmed/31709729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201809571
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