Cobalt protoporphyrin IX increases endogenous G‐CSF and mobilizes HSC and granulocytes to the blood

Granulocyte colony‐stimulating factor (G‐CSF) is used in clinical practice to mobilize cells from the bone marrow to the blood; however, it is not always effective. We show that cobalt protoporphyrin IX (CoPP) increases plasma concentrations of G‐CSF, IL‐6, and MCP‐1 in mice, triggering the mobiliza...

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Pubblicato in:EMBO Mol Med
Autori principali: Szade, Agata, Szade, Krzysztof, Nowak, Witold N, Bukowska‐Strakova, Karolina, Muchova, Lucie, Gońka, Monika, Żukowska, Monika, Cieśla, Maciej, Kachamakova‐Trojanowska, Neli, Rams‐Baron, Marzena, Ratuszna, Alicja, Dulak, Józef, Józkowicz, Alicja
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2019
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6895613/
https://ncbi.nlm.nih.gov/pubmed/31709729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201809571
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