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Human iPSCs-Derived Endothelial Cells with Mutation in HNF1A as a Model of Maturity-Onset Diabetes of the Young

Patients with HNF1A-maturity-onset diabetes of the young (MODY) often develop endothelial dysfunction and related microvascular complications, like retinopathy. As the clinical phenotype of HNF1A-MODY diabetes varies considerably, we used human induced pluripotent stem cells (hiPSCs) from two health...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Kachamakova-Trojanowska, Neli, Stepniewski, Jacek, Dulak, Jozef
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6912300/
https://ncbi.nlm.nih.gov/pubmed/31739614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8111440
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