B-cell–specific IRF4 deletion accelerates chronic lymphocytic leukemia development by enhanced tumor immune evasion

Chronic lymphocytic leukemia (CLL) is a heterogenous disease that is highly dependent on a cross talk of CLL cells with the microenvironment, in particular with T cells. T cells derived from CLL patients or murine CLL models are skewed to an antigen-experienced T-cell subset, indicating a certain de...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Asslaber, Daniela, Qi, Yuan, Maeding, Nicole, Steiner, Markus, Denk, Ursula, Höpner, Jan Philip, Hartmann, Tanja Nicole, Zaborsky, Nadja, Greil, Richard, Egle, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2019
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6895374/
https://ncbi.nlm.nih.gov/pubmed/31537531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019000973
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