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MORC2 regulates DNA damage response through a PARP1-dependent pathway

Microrchidia family CW-type zinc finger 2 (MORC2) is a newly identified chromatin remodeling enzyme with an emerging role in DNA damage response (DDR), but the underlying mechanism remains largely unknown. Here, we show that poly(ADP-ribose) polymerase 1 (PARP1), a key chromatin-associated enzyme re...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Zhang, Lin, Li, Da-Qiang
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6895267/
https://ncbi.nlm.nih.gov/pubmed/31616951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz545
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