Glycocalyx breakdown is increased in African children with cerebral and uncomplicated falciparum malaria

Cerebral malaria (CM) from Plasmodium falciparum infection is associated with endothelial dysfunction and parasite sequestration. The glycocalyx (GCX), a carbohydrate-rich layer lining the endothelium, is crucial in vascular homeostasis. To evaluate the role of its loss in the pathogenesis of pediat...

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Bibliographic Details
Published in:FASEB J
Main Authors: Yeo, Tsin W., Bush, Peggy A., Chen, Youwei, Young, Sarah P., Zhang, Haoyue, Millington, David S., Granger, Donald L., Mwaikambo, Esther D., Anstey, Nicholas M., Weinberg, J. Brice
Format: Artigo
Language:Inglês
Published: Federation of American Societies for Experimental Biology 2019
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6894053/
https://ncbi.nlm.nih.gov/pubmed/31658834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201901048RR
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