Glycocalyx breakdown is increased in African children with cerebral and uncomplicated falciparum malaria

Cerebral malaria (CM) from Plasmodium falciparum infection is associated with endothelial dysfunction and parasite sequestration. The glycocalyx (GCX), a carbohydrate-rich layer lining the endothelium, is crucial in vascular homeostasis. To evaluate the role of its loss in the pathogenesis of pediat...

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Detalles Bibliográficos
Publicado en:FASEB J
Autores principales: Yeo, Tsin W., Bush, Peggy A., Chen, Youwei, Young, Sarah P., Zhang, Haoyue, Millington, David S., Granger, Donald L., Mwaikambo, Esther D., Anstey, Nicholas M., Weinberg, J. Brice
Formato: Artigo
Lenguaje:Inglês
Publicado: Federation of American Societies for Experimental Biology 2019
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6894053/
https://ncbi.nlm.nih.gov/pubmed/31658834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201901048RR
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