Glycocalyx breakdown is increased in African children with cerebral and uncomplicated falciparum malaria

Cerebral malaria (CM) from Plasmodium falciparum infection is associated with endothelial dysfunction and parasite sequestration. The glycocalyx (GCX), a carbohydrate-rich layer lining the endothelium, is crucial in vascular homeostasis. To evaluate the role of its loss in the pathogenesis of pediat...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Yeo, Tsin W., Bush, Peggy A., Chen, Youwei, Young, Sarah P., Zhang, Haoyue, Millington, David S., Granger, Donald L., Mwaikambo, Esther D., Anstey, Nicholas M., Weinberg, J. Brice
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6894053/
https://ncbi.nlm.nih.gov/pubmed/31658834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201901048RR
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