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Glycocalyx breakdown is increased in African children with cerebral and uncomplicated falciparum malaria

Cerebral malaria (CM) from Plasmodium falciparum infection is associated with endothelial dysfunction and parasite sequestration. The glycocalyx (GCX), a carbohydrate-rich layer lining the endothelium, is crucial in vascular homeostasis. To evaluate the role of its loss in the pathogenesis of pediat...

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Dettagli Bibliografici
Pubblicato in:FASEB J
Autori principali: Yeo, Tsin W., Bush, Peggy A., Chen, Youwei, Young, Sarah P., Zhang, Haoyue, Millington, David S., Granger, Donald L., Mwaikambo, Esther D., Anstey, Nicholas M., Weinberg, J. Brice
Natura: Artigo
Lingua:Inglês
Pubblicazione: Federation of American Societies for Experimental Biology 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6894053/
https://ncbi.nlm.nih.gov/pubmed/31658834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201901048RR
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