Dimethylarginines: Endogenous Inhibitors of Nitric Oxide Synthesis in Children With Falciparum Malaria

Background. Nitric oxide (NO) bioavailability is impaired in children and adults with severe falciparum malaria (SM). Asymmetric-dimethylarginine (ADMA) limits NO production by inhibiting NO synthase and is increased in adult SM. The role of ADMA in the pathogenesis of childhood SM is unknown. Metho...

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Bibliographic Details
Main Authors: Weinberg, Joe Brice, Yeo, Tsin W., Mukemba, Jackson P., Florence, Salvatore M., Volkheimer, Alicia D., Wang, Hao, Chen, Youwei, Rubach, Matthew, Granger, Donald L., Mwaikambo, Esther D., Anstey, Nicholas M.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2014
Subjects:
Major Articles and Brief Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4192051/
https://ncbi.nlm.nih.gov/pubmed/24620026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiu156
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