Increased Asymmetric Dimethylarginine in Severe Falciparum Malaria: Association with Impaired Nitric Oxide Bioavailability and Fatal Outcome

Asymmetrical dimethylarginine (ADMA), an endogenous inhibitor of nitric oxide synthase (NOS), is a predictor of mortality in critical illness. Severe malaria (SM) is associated with decreased NO bioavailability, but the contribution of ADMA to the pathogenesis of impaired NO bioavailability and adve...

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Detalhes bibliográficos
Main Authors: Yeo, Tsin W., Lampah, Daniel A., Tjitra, Emiliana, Gitawati, Retno, Darcy, Christabelle J., Jones, Catherine, Kenangalem, Enny, McNeil, Yvette R., Granger, Donald L., Lopansri, Bert K., Weinberg, J. Brice, Price, Ric N., Duffull, Stephen B., Celermajer, David S., Anstey, Nicholas M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858698/
https://ncbi.nlm.nih.gov/pubmed/20421938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000868
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