Increased Asymmetric Dimethylarginine in Severe Falciparum Malaria: Association with Impaired Nitric Oxide Bioavailability and Fatal Outcome

Asymmetrical dimethylarginine (ADMA), an endogenous inhibitor of nitric oxide synthase (NOS), is a predictor of mortality in critical illness. Severe malaria (SM) is associated with decreased NO bioavailability, but the contribution of ADMA to the pathogenesis of impaired NO bioavailability and adve...

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Autori principali: Yeo, Tsin W., Lampah, Daniel A., Tjitra, Emiliana, Gitawati, Retno, Darcy, Christabelle J., Jones, Catherine, Kenangalem, Enny, McNeil, Yvette R., Granger, Donald L., Lopansri, Bert K., Weinberg, J. Brice, Price, Ric N., Duffull, Stephen B., Celermajer, David S., Anstey, Nicholas M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2010
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858698/
https://ncbi.nlm.nih.gov/pubmed/20421938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000868
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