Glycocalyx Breakdown Is Associated With Severe Disease and Fatal Outcome in Plasmodium falciparum Malaria

BACKGROUND: Interactions between the endothelium and infected erythrocytes play a major role in the pathogenesis of falciparum malaria, with microvascular dysfunction and parasite sequestration associated with worsening outcomes. The glycocalyx is a carbohydrate-rich layer that lines the endothelium...

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Bibliographic Details
Published in:Clin Infect Dis
Main Authors: Yeo, Tsin W, Weinberg, J Brice, Lampah, Daniel A, Kenangalem, Enny, Bush, Peggy, Chen, Youwei, Price, Richard N, Young, Sarah, Zhang, Hao Y, Millington, David, Granger, Donald L, Anstey, Nicholas M
Format: Artigo
Language:Inglês
Published: Oxford University Press 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6821254/
https://ncbi.nlm.nih.gov/pubmed/30753363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/ciz038
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