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Sex Differences and Drug Dose Influence the Role of the α7 Nicotinic Acetylcholine Receptor in the Mouse Dextran Sodium Sulfate-Induced Colitis Model

INTRODUCTION: α7 nicotinic acetylcholine receptors (nAChRs) play an important role in vagus nerve-based cholinergic anti-inflammatory effects. This study was designed to assess the role of α7 nAChRs in dextran sodium sulfate (DSS)-induced colitis in male and female mouse. We first compared disease a...

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Detalhes bibliográficos
Publicado no:Nicotine Tob Res
Main Authors: AlSharari, Shakir D., Bagdas, Deniz, Akbarali, Hamid I., Lichtman, Patraic A., Raborn, Erinn S., Cabral, Guy A., Carroll, F. Ivy, McGee, Elizabeth A., Damaj, M. Imad
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6894014/
https://ncbi.nlm.nih.gov/pubmed/27639096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ntr/ntw245
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