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The interaction between alpha 7 nicotinic acetylcholine receptor and nuclear peroxisome proliferator-activated receptor-α represents a new antinociceptive signaling pathway in mice

Recently, α7 nicotinic acetylcholine receptors (nAChRs), primarily activated by binding of orthosteric agonists, represent a target for anti-inflammatory and analgesic drug development. These receptors may also be modulated by positive allosteric modulators (PAMs), ago-allosteric ligands (ago-PAMs),...

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Detalhes bibliográficos
Publicado no:Exp Neurol
Main Authors: Donvito, Giulia, Bagdas, Deniz, Toma, Wisam, Rahimpour, Elnaz, Jackson, Asti, Meade, Julie A., AlSharari, Shakir, Kulkarni, Abhijit R., Carroll, F. Ivy, Lichtman, Aron H., Papke, Roger L., Thakur, Ganesh A., Damaj, M. Imad
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5558428/
https://ncbi.nlm.nih.gov/pubmed/28606623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2017.06.014
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