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Blockade of nicotinic acetylcholine receptor enhances the responsiveness to bupropion in the mouse forced swim test

The objective of the present study is to investigate the role of α4, α5, α6 or β2 nAChR subunits in the antidepressant-like effect of bupropion. Adult male mice were treated with subcutaneous acute doses of bupropion (3 and 10 mg/kg) 30 min before the forced swim test (FST) in α4, α5, α6, or β2 nACh...

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Detalhes bibliográficos
Publicado no:Behav Brain Res
Main Authors: Bagdas, Deniz, AlSharari, Shakir, Roni, Monzurul A., Campbell, Vera C., Muldoon, Pretal P., Carroll, F. Ivy, Damaj, M. Imad
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6324988/
https://ncbi.nlm.nih.gov/pubmed/30552947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2018.12.027
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