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Blockade of nicotinic acetylcholine receptor enhances the responsiveness to bupropion in the mouse forced swim test

The objective of the present study is to investigate the role of α4, α5, α6 or β2 nAChR subunits in the antidepressant-like effect of bupropion. Adult male mice were treated with subcutaneous acute doses of bupropion (3 and 10 mg/kg) 30 min before the forced swim test (FST) in α4, α5, α6, or β2 nACh...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Behav Brain Res
Hauptverfasser: Bagdas, Deniz, AlSharari, Shakir, Roni, Monzurul A., Campbell, Vera C., Muldoon, Pretal P., Carroll, F. Ivy, Damaj, M. Imad
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6324988/
https://ncbi.nlm.nih.gov/pubmed/30552947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2018.12.027
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