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Non-canonical radical SAM enzyme chemistry learned from diphthamide biosynthesis
Radical S-adenosylmethionine (SAM) enzymes are a superfamily of enzymes that use SAM and reduced [4Fe-4S] cluster to generate a 5′-deoxyadenosyl radical to catalyze numerous challenging reactions. We have reported a type of non-canonical radical SAM enzymes in the diphthamide biosynthesis pathway. T...
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| Publicado no: | Biochemistry |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6893904/ https://ncbi.nlm.nih.gov/pubmed/29708734 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b00287 |
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