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Diphthamide biosynthesis requires an Fe-S enzyme-generated organic radical
Archaeal and eukaryotic translation elongation factor 2 contain a unique posttranslationally modified histidine residue called “diphthamide”, the target of diphtheria toxin. The biosynthesis of diphthamide were proposed to involve three steps, with the first step being the formation of a C-C bond be...
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| Hauptverfasser: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3006227/ https://ncbi.nlm.nih.gov/pubmed/20559380 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09138 |
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