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Polyphosphate, Zn(2+) and high molecular weight kininogen modulate individual reactions of the contact pathway of blood clotting

BACKGROUND: Inorganic polyphosphate modulates the contact pathway of blood clotting, which is implicated in thrombosis and inflammation. Polyphosphate polymer lengths are highly variable, with shorter polymers (approximately 60–100 phosphates) secreted from human platelets, and longer polymers (up t...

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Detalhes bibliográficos
Publicado no:J Thromb Haemost
Main Authors: Wang, Yuqi, Ivanov, Ivan, Smith, Stephanie A., Gailani, David, Morrissey, James H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6893101/
https://ncbi.nlm.nih.gov/pubmed/31420909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.14612
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