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Polyphosphate and RNA Differentially Modulate the Contact Pathway of Blood Clotting

The contact pathway of the plasma clotting cascade is dispensable for normal hemostasis, but contributes to thrombosis and serves as a bridge between inflammation and coagulation. This pathway is triggered upon exposure of plasma to certain anionic polymers and artificial surfaces. Recently, extrace...

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Veröffentlicht in:J Biol Chem
Hauptverfasser: Gajsiewicz, Joshua M., Smith, Stephanie A., Morrissey, James H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5290954/
https://ncbi.nlm.nih.gov/pubmed/28007958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.754325
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