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Ability of Polyphosphate and Nucleic Acids to Trigger Blood Clotting: Some Observations and Caveats

Polyphosphate plays several roles in coagulation and inflammation, while extracellular DNA and RNA are implicated in thrombosis and as disease biomarkers. We sought to compare the procoagulant activities of polyphosphate versus DNA or RNA isolated from mammalian cells. In a recent study, we found th...

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Detalhes bibliográficos
Publicado no:Front Med (Lausanne)
Main Authors: Smith, Stephanie A., Gajsiewicz, Joshua M., Morrissey, James H.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5913279/
https://ncbi.nlm.nih.gov/pubmed/29719836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmed.2018.00107
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