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BIIB093 (IV glibenclamide): an investigational compound for the prevention and treatment of severe cerebral edema
INTRODUCTION: Brain swelling due to edema formation is a major cause of neurological deterioration and death in patients with large hemispheric infarction (LHI) and severe traumatic brain injury (TBI), especially contusion-TBI. Preclinical studies have shown that SUR1-TRPM4 channels play a critical...
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| Publicado no: | Expert Opin Investig Drugs |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6893098/ https://ncbi.nlm.nih.gov/pubmed/31623469 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/13543784.2019.1681967 |
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