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Profile of intravenous glyburide for the prevention of cerebral edema following large hemispheric infarction: evidence to date
Glyburide (also known as glibenclamide) is a second-generation sulfonylurea drug that inhibits sulfonylurea receptor 1 (Sur1) at nanomolar concentrations. Long used to target K(ATP) (Sur1–Kir6.2) channels for the treatment of diabetes mellitus type 2, glyburide was recently repurposed to target Sur1...
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| Publicado no: | Drug Des Devel Ther |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove Medical Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6101021/ https://ncbi.nlm.nih.gov/pubmed/30147301 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S150043 |
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