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BIIB093 (intravenous glibenclamide) for the prevention of severe cerebral edema

BACKGROUND: Vasogenic edema in the setting of acute ischemic stroke can be attributed to the opening of transient receptor potential 4 channels, which are expressed in the setting of injury and regulated by sulfonylurea receptor 1 (SUR1) proteins. Glibenclamide, also known as glyburide, RP-1127, Cir...

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Podrobná bibliografie
Vydáno v:Surg Neurol Int
Hlavní autoři: Griepp, Daniel W., Lee, Jason, Moawad, Christina M., Davati, Cyrus, Runnels, Juliana, Fiani, Brian
Médium: Artigo
Jazyk:Inglês
Vydáno: Scientific Scholar 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7982107/
https://ncbi.nlm.nih.gov/pubmed/33767884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.25259/SNI_933_2020
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