Type I-F CRISPR-Cas resistance against virulent phages results in abortive infection and provides population-level immunity

Type I CRISPR-Cas systems are abundant and widespread adaptive immune systems in bacteria and can greatly enhance bacterial survival in the face of phage infection. Upon phage infection, some CRISPR-Cas immune responses result in bacterial dormancy or slowed growth, which suggests the outcomes for i...

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Pubblicato in:Nat Commun
Autori principali: Watson, Bridget N. J., Vercoe, Reuben B., Salmond, George P. C., Westra, Edze R., Staals, Raymond H. J, Fineran, Peter C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6892833/
https://ncbi.nlm.nih.gov/pubmed/31797922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13445-2
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