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Different genetic and morphological outcomes for phages targeted by single or multiple CRISPR-Cas spacers
CRISPR-Cas systems provide bacteria and archaea with adaptive immunity against genetic invaders, such as bacteriophages. The systems integrate short sequences from the phage genome into the bacterial CRISPR array. These ‘spacers’ provide sequence-specific immunity but drive natural selection of evol...
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| Publicado no: | Philos Trans R Soc Lond B Biol Sci |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Royal Society
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6452268/ https://ncbi.nlm.nih.gov/pubmed/30905290 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2018.0090 |
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