Spacer capture and integration by a type I-F Cas1–Cas2-3 CRISPR adaptation complex

CRISPR-Cas adaptive immune systems capture DNA fragments from invading bacteriophages and plasmids and integrate them as spacers into bacterial CRISPR arrays. In type I-E and II-A CRISPR-Cas systems, this adaptation process is driven by Cas1–Cas2 complexes. Type I-F systems, however, contain a uniqu...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Fagerlund, Robert D., Wilkinson, Max E., Klykov, Oleg, Barendregt, Arjan, Pearce, F. Grant, Kieper, Sebastian N., Maxwell, Howard W. R., Capolupo, Angela, Heck, Albert J. R., Krause, Kurt L., Bostina, Mihnea, Scheltema, Richard A., Staals, Raymond H. J., Fineran, Peter C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5495228/
https://ncbi.nlm.nih.gov/pubmed/28611213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1618421114
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