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Spider Knottin Pharmacology at Voltage-Gated Sodium Channels and Their Potential to Modulate Pain Pathways

Voltage-gated sodium channels (Na(V)s) are a key determinant of neuronal signalling. Neurotoxins from diverse taxa that selectively activate or inhibit Na(V) channels have helped unravel the role of Na(V) channels in diseases, including chronic pain. Spider venoms contain the most diverse array of i...

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Dades bibliogràfiques
Publicat a:Toxins (Basel)
Autors principals: Dongol, Yashad, Cardoso, Fernanda C., Lewis, Richard J.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6891507/
https://ncbi.nlm.nih.gov/pubmed/31671792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins11110626
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