Mechanosensing during directed cell migration requires dynamic actin polymerization at focal adhesions

The mechanical properties of a cell’s microenvironment influence many aspects of cellular behavior, including cell migration. Durotaxis, the migration toward increasing matrix stiffness, has been implicated in processes ranging from development to cancer. During durotaxis, mechanical stimulation by...

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Veröffentlicht in:J Cell Biol
Hauptverfasser: Puleo, Julieann I., Parker, Sara S., Roman, Mackenzie R., Watson, Adam W., Eliato, Kiarash Rahmani, Peng, Leilei, Saboda, Kathylynn, Roe, Denise J., Ros, Robert, Gertler, Frank B., Mouneimne, Ghassan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Rockefeller University Press 2019
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Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6891092/
https://ncbi.nlm.nih.gov/pubmed/31594807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201902101
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