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Mechanosensing during directed cell migration requires dynamic actin polymerization at focal adhesions

The mechanical properties of a cell’s microenvironment influence many aspects of cellular behavior, including cell migration. Durotaxis, the migration toward increasing matrix stiffness, has been implicated in processes ranging from development to cancer. During durotaxis, mechanical stimulation by...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Puleo, Julieann I., Parker, Sara S., Roman, Mackenzie R., Watson, Adam W., Eliato, Kiarash Rahmani, Peng, Leilei, Saboda, Kathylynn, Roe, Denise J., Ros, Robert, Gertler, Frank B., Mouneimne, Ghassan
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6891092/
https://ncbi.nlm.nih.gov/pubmed/31594807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201902101
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