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Two Distinct Actin Networks Mediate Traction Oscillations to Confer Focal Adhesion Mechanosensing

Focal adhesions (FAs) are integrin-based transmembrane assemblies that connect a cell to its extracellular matrix (ECM). They are mechanosensors through which cells exert actin cytoskeleton-mediated traction forces to sense the ECM stiffness. Interestingly, FAs themselves are dynamic structures that...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Wu, Zhanghan, Plotnikov, Sergey V., Moalim, Abdiwahab Y., Waterman, Clare M., Liu, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5340160/
https://ncbi.nlm.nih.gov/pubmed/28256237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.12.035
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