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Mechanism of Focal Adhesion Kinase Mechanosensing
Mechanosensing at focal adhesions regulates vital cellular processes. Here, we present results from molecular dynamics (MD) and mechano-biochemical network simulations that suggest a direct role of Focal Adhesion Kinase (FAK) as a mechano-sensor. Tensile forces, propagating from the membrane through...
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| Publicado no: | PLoS Comput Biol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4636223/ https://ncbi.nlm.nih.gov/pubmed/26544178 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004593 |
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